CHEMISTRY 519

Biochemistry and Molecular Biology:

An Introduction for Chemists

Professor Peter Z. Qin

Professor Richard Roberts

last updated January 20, 2006

SPRING SEMESTER 2006 COURSE SYLLABUS

LECTURE: MW; 9:30 a.m.- 10:45 a.m.

Location: OCW 214

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Instructor & TA
Course Materials
Lecture Exam Information
Schedule of Lectures
Homework Problems and Reading List

INSTRUCTIONAL STAFF

Course Lecturer:	Prof. Peter Qin
Office:	Stabler Hall (LJS) 251
Telephone:	(213) 821-2461
Email:	pzq@usc.edu
Office Hours:	10:45 - 11:45 MW or by appt.

Course Lecturer:

Prof. Richard Roberts

Office:

RTH 507

Telephone:
(213) 740-7036

Email:

richard.roberts@usc.edu

Office Hours:

TBA

COURSE MATERIALS:

TEXT BOOK

Biochemistry, 5th Edition by Berg, Tymoczko- Stryer (W.H. Freeman, New York, 2002.

We will supplement the text with material drawn from the recent literature, and other sources. In addition, the following books will be kept on reserve for class use:

LOAN PERIOD AUTHOR TITLE CALL# LOCATION

Libuse: 2 hrs Walsh, Christopher Enzymatic Reaction Mechanism QP601.W23 SSC

Libuse: 2 hrs Dryer, Robert Experimental Biochemistry QP519.D79 SSC

Libuse: 2 hrs Segel, Irwin H. Biochemical Calculations QD415.3.54 SSC

Libuse: 2 hrs Cantor & Schimmel
Biophysical chemistry

QH345.C36
SSC

Libuse: 2 hrs Segel, Irwin H. Enzyme Kinetics ? SSC

GRADING:

There will be one midterm (150 points) and a final exam (160 points). There will be one term paper (75 points for written part, 75 points for oral presentation) due in class. The point distribution will be:
```
Problem Sets    140
Term Papers     150
Midterm         150
Final           160
Maximum         600
```

LECTURE EXAMINATION INFORMATION:

MAKEUP EXAMS
No makeup exams will be given.
FINAL LECTURE EXAM
Exam on Monday, May 8. (IN CLASS, CLOSED BOOK) (Time to be announced)
DROP DATES:
January 27 is the last day to drop this course without a mark of W. April 7 is the last day to drop this course with a grade of W.
ACADEMIC INTEGRITY
It is expected that all students will follow the rules of academic integrity as set forward by the University. Cheating on an examination or changing the answers of a returned exam are serious violations of academic integrity and may result in a mandatory grade of F for the course.

SCHEDULE OF LECTURES

(topics subjected to changes)

Date Topic

Lecture # - Prof

Read Text

Mon, January 9

Organizational Meeting

1 - PZQ & RR

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Wed, January 11

Domains of "Biochemistry";

Amino Acids I

2 - PZQ

S-1; 3

Mon, January 16

UNIVERSITY HOLIDAY

-

Break

Wed, January 18

Amino Acids II

3 - PZQ

S-3

Mon, January 23

Peptides I
(Structures)

4 - PZQ

S-3

Wed, January 25

Peptides II
(Synthesis)

5 - PZQ

S-4; 29

Mon, January 30

Proteins I

6 - PZQ

S-4

Wed, February 1

Proteins II

7 - PZQ

S-4

Mon, February 6

DNA I

8 - PZQ

S-5

Wed, February 8

DNA II 9 - PZQ S-5

Mon, February 13

RNA 10 - PZQ S-5;28

Wed, February 15

Lipids & Membranes
11 - PZQ S-12

Mon, February 20

UNIVERSITY HOLIDAY

-

Break

Wed, February 22

MIDTERM EXAMINATION

Good Luck!

Mon, February 27

Enzymes I

12 - RR

TBA

Wed, March 1

Enzymes II

13 - RR

TBA

Mon, March 6

Enzymes III

14 - RR

TBA

Wed, March 8

Enzymes IV

15 - RR

TBA

Mon, March 13

SPRING RECESS

----Spring Recess----

Wed, March 15

SPRING RECESS

----Spring Recess----

Mon, March 20

TBA

13 - RR

TBA

Wed, March 22

TBA

17 - RR

TBA

Mon, March 27

TBA

18 - RR

TBA

Wed, March 29

TBA

19 - RR

TBA

Mon, April 3

TBA

20 - RR

TBA

Wed, April 5

TBA

21 - RR

TBA

Mon, April 10

Oral Papers #I

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Wed, April 12

Oral Papers #II

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Mon, April 17

Oral Papers #III

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Wed, April 19

Oral Papers #IV

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Mon, April 24

Oral Papers #V

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Wed, April 26

Review (for Final Exam)

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Mon, May 8

FINAL EXAM

HOMEWORK PROBLEMS

BIOCHEMISTRY, 5TH EDITION BY BERG- TYMOCZKO-STRYER

"End-of-chapter" problems are recommended as self-exercises.

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