3rd Annual iPIDD Retreat

Event Information

Location

Pickwick Gardens Burbank, CA

Date	September 14, 2007

Time	8:00 am - 4:30 pm

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Schedule for iPIDD Retreat, June 17, 2005

 

8:00 – 9:00	Arrival, poster setup, breakfast
9:00 – 9:20	Welcoming Remarks (Dean Vanderveen) (Profs. Ian Haworth and Charles McKenna)
Session 1	Chairs: James Sanchez (PSCI) & Larryn Peterson (CHEM)

9:20 – 9:40
	Lifei Liu (PSCI) “Allopregnanolone: neurogenic properties and its therapeutic potential to treat Alzheimer’s Disease”
9:40 – 10:00
	Joy Lynn Bala (CHEM) “Fluorescently labeled risedronate and related analogs: novel synthesis and evaluation as imaging probes”
10:00 – 10:20
	Liya Xu (PSCI) “Cysteine scanning of transmembrane domain 10 of the human dipeptide transporter: implications for substrate transport”

10:20 – 10:40
	Victor Hadi (CHEM) “Current progress in total synthesis of palmerolide A”
10:45 – 11:00	Coffee Break
Session 2	Chairs: Melissa Millard (PSCI) & James Hogan (CHEM)

11:00 – 11:20
	James Adams (PSCI)    “New morphinans from a California plant”
11:20 – 11:40
	Gian Paola Grant (CHEM) “Using site-directed spin labeling to study the dynamics of substrate docking in Group I intron ribozyme”
11:40 – 12:00
	Zahrah Zawahir (PSCI) “Mammalian base excision repair as a novel drug target”

12:10 – 1:15	iPIDD group photo, Lunch, Brainstorming session
Session 3	Chairs: Anna Popova (CHEM)
1:20 – 1:40
	Tim Gallaher (PSCI) “Mass spectrometry:  protein identification, post-translational modifications”

1:40 – 2:00
	Thomas Upton (CHEM) “Synthesis and pKa values of methylenebisphosphonic acids: a dNTP analog toolkit”
2:00 – 2:20
	Xiaoying Chen (PSCI) “Oral protein drug delivery, unsolved puzzle?”
2:20 - 2:40	Christopher Sucato (CHEM) “Presteady state kinetic analysis of DNA polymerase beta utilizing novel dNTP analogs”
Poster Session	Chairs: Brian Sutch (PSCI) & Daniel Ahn (CHEM)

2:50 – 3:10
	Two-minute oral presentations from each poster presenter
3:10 – 4:00	Open discussion of posters
4:00 - 4:10
	Closing Remarks (James Sanchez and Larryn Peterson)

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List of posters:

Daniel Ahn (CHEM)

“Predicting the relative activities of nitrogen-containing bisphosphonates in silico”

Nurmamet Amet (PSCI)

“Comparing in vitro bioactivities of fusion proteins with the Tf domain at the N- or C-terminus”

Matt Franzman (CHEM)

“Spectroscopic evidence of the formation of Goldfingers”

James Hogan (PSCI)

“Modeling, synthetic, crystallographic, and activity studies of novel bisphosphonates as inhibitors of farnesyl pyrophosphate synthase”

Jamie Jarusiewicz (CHEM)

“N-heterocyclic carbene ligand-palladium complex catalyzed asymmetric acetoxylation of allylic analogs”

Larryn Peterson (CHEM)

“Enhancing cidofovir oral bioavailability: insights from SAR studies of novel peptidomimetic prodrugs”

Chi Pham (CHEM)

“Design and synthesis of foscarnet amino acid conjugate prodrugs”

Anna Popova (CHEM)

“Probing local DNA dynamics using sequence-independent nitroxide probes”

James Sanchez (PSCI)

“Application of a versatile and efficient gene targeting system for the genomic mining of secondary metabolites in Aspergillus nidulans"

Brian Sutch (PSCI)

“Nucleic acid aptamer-protein interaction database”

Travis Williams (CHEM)

“Copper-catalyzed oxidation reactions for synthesis of actin polymerizing inhibitors”

Hosted by: USC Departments of Chemistry and Pharmaceutical Sciences